Prasugrel, a new medicine for preventing blockages in the arteries
نویسندگان
چکیده
Prasugrel {systematic name: 5-[(2-cyclo-propyl-carbon-yl)(2-fluoro-phen-yl)meth-yl]-4,5,6,7-tetra-hydro-thieno[3,2-c]pyridin-2-yl acetate}, C(20)H(20)FNO(3)S, is a new third-generation thienopyridine which was recently approved for clinical use as a more potent blocker of the platelet P2Y(12) receptor than clopidogrel, which was previously used for this purpose. The mol-ecule features a tetra-hydro-thienopyridine system with the tetra-hydro-pyridine ring showing a half-chair conformation; the dihedral angle formed by the the planes of the benzene and thio-phene rings is 83.17 (3)°.
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